Abstract
Acinetobacter baumannii adapts to different environmental conditions by expressing complex regulatory circuitry. Recent studies revealed that this circuitry includes regulatory factors that control the emergence of distinct bacterial subpopulations, which are critical for the capacity of this pathogen to persist in medical settings and cause infections in compromised hosts.
Keywords:
Transcriptional regulation; bacterial subpopulations; persistence; resistance; virulence.
Copyright © 2018 Elsevier Ltd. All rights reserved.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Acinetobacter Infections / microbiology*
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Acinetobacter baumannii / drug effects
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Acinetobacter baumannii / genetics
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Acinetobacter baumannii / pathogenicity*
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Acinetobacter baumannii / physiology*
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Anti-Bacterial Agents / pharmacology
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Drug Resistance, Bacterial
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Gene Expression Regulation, Bacterial
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Genes, Bacterial
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Genome, Bacterial
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Host Specificity
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Virulence
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Virulence Factors
Substances
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Anti-Bacterial Agents
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Virulence Factors