Reshaping drug development using 3D printing

Drug Discov Today. 2018 Aug;23(8):1547-1555. doi: 10.1016/j.drudis.2018.05.025. Epub 2018 May 24.

Abstract

The pharmaceutical industry stands on the brink of a revolution, calling for the recognition and embracement of novel techniques. 3D printing (3DP) is forecast to reshape the way in which drugs are designed, manufactured, and used. Although a clear trend towards personalised fabrication is perceived, here we accentuate the merits and shortcomings of each technology, providing insights into aspects such as the efficiency of production, global supply, and logistics. Contemporary opportunities for 3DP in drug discovery and pharmaceutical development and manufacturing are unveiled, offering a forward-looking view on its potential uses as a digitised tool for personalised dispensing of drugs.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Drug Compounding
  • Drug Discovery / methods*
  • Humans
  • Molecular Structure
  • Pharmaceutical Preparations / chemical synthesis*
  • Pharmaceutical Preparations / supply & distribution
  • Printing, Three-Dimensional*
  • Structure-Activity Relationship

Substances

  • Pharmaceutical Preparations