Evolutive echocardiographic changes in cardiac amyloidosis: Look at the whole picture

Echocardiography. 2018 Jul;35(7):1042-1044. doi: 10.1111/echo.14033. Epub 2018 May 25.

Abstract

Doppler echocardiogram provides not only structural information about heart chambers, valves and pericardium but also contributes to functional assessment. A unique feature of this assessment is its variability, not only due to heart disease course but also related to extracardiac conditions. We present a case of primary amyloidosis with two atypical characteristics: left ventricular outflow obstruction and low-grade diastolic dysfunction. Nevertheless, a more typical picture of cardiac amyloidosis was observed in the evolution of the disease coinciding with a second cardiac stressor, emphasizing the necessity of not focusing our attention exclusively to the heart.

Keywords: Doppler echocardiography; cardiac amyloidosis; diastolic function; dynamic left ventricular obstruction; hypertension.

Publication types

  • Case Reports
  • Video-Audio Media

MeSH terms

  • Amyloidosis / complications
  • Amyloidosis / diagnosis*
  • Amyloidosis / physiopathology
  • Cardiomyopathies / complications
  • Cardiomyopathies / diagnosis*
  • Cardiomyopathies / physiopathology
  • Echocardiography, Doppler / methods*
  • Humans
  • Male
  • Middle Aged
  • Ventricular Function, Left / physiology*
  • Ventricular Outflow Obstruction / diagnosis*
  • Ventricular Outflow Obstruction / etiology
  • Ventricular Outflow Obstruction / physiopathology