Leukemic retinophaty, the first manifestation in a case of acute myelogenous leukemia

Rom J Ophthalmol. 2018 Jan-Mar;62(1):72-77.

Abstract

A 42-year-old woman, without a specific medical history presented at the Department of Emergency Ophthalmology accusing marked decrease of vision for the left eye (VA 1/ 100). The eye examination revealed an optic neuropathy with multiple retinal hemorrhages at the level of both eyes, but more acutely on the left eye. The brain computer tomography (CT) excluded the suspicion of increasing intracranial pressure. The common blood tests such as complete blood count (CBC), erythrocyte sedimentation rate, and inflammatory markers raised a high suspicion of a malignant haematological disease.

Keywords: LAM3-Acute promyelocytic leukemia; all-trans retinoic acid; bone marrow aspiration and biopsy; disseminated intravascular coagulation (DIC); leukemic retinopathy; sepsis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Disseminated Intravascular Coagulation
  • Female
  • Humans
  • Leukemia, Myeloid, Acute
  • Leukemia, Promyelocytic, Acute / complications*
  • Leukemia, Promyelocytic, Acute / diagnosis
  • Optic Nerve Diseases / etiology*
  • Retinal Hemorrhage