Effect of β-hydroxy-β-methylbutyrate acid on meat performance traits and selected indicators of humoral immunity in goats

Jpn J Vet Res. 2016 Nov;64(4):247-256.

Abstract

The aim of this study was to determine the effect of β-hydroxy-β-methylbutyrate acid, on parameters of meat performance in goats as well as on selected parameters of non-specific humoral defense. An experiment was performed on 24 Alpine kids divided into two equal groups: I - control and II - experimental. Over a period of 60 days, the animals were fed an HMB-supplemented diet. The following meat performance parameters were determined: body weight, daily gains, growth rate, the dimensions of musculus longissimus dorsi (m.l.d.) sections and fat thickness over the loin "eye". Selected indicators of non-specific humoral immunity were determined in the blood serum of kids: lysozyme activity, ceruloplasmin activity and gamma globulin content. It was found that the kids administered HMB had a significantly higher body weight on days 30 and 60 of the experiment compared to the control group. The kids in this group also had a significantly more favorable musculature development. Simultaneously, a significant impact of HIMB on the examined immunological indices was found. The significance of differences in relation to the control group was confirmed statistically for lysozyme activity and ceruloplasmin activity on days 30 and 60, while the content of gammaglobulins was confirmed statistically on days 15, 30 and 60 of the study. It was also found that the addition of HMB had a stimulating impact on immunity and growth rate as well as on the development of muscles. It is thus justified to administer HMB to early-weaned kids to enhance their rearing parameters.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Animal Feed / analysis*
  • Animal Nutritional Physiological Phenomena
  • Animals
  • Diet / veterinary*
  • Goats / immunology
  • Goats / physiology
  • Immunity, Humoral / drug effects*
  • Meat / standards*
  • Valerates / administration & dosage*
  • Valerates / pharmacology

Substances

  • Valerates
  • beta-hydroxyisovaleric acid