Prediction of preeclampsia developing at term

Ginekol Pol. 2018;89(4):217-20. doi: 10.5603/GP.a2018.0037.

Abstract

Preterm preeclampsia (PE), occurring at < 37 weeks' gestation, can be predicted from as early as 11-13 weeks and prevented with the use of aspirin. In contrast, term PE, which is more common than preterm-PE and it can be associated with important maternal morbidity and mortality, cannot be effectively predicted at 11-13 weeks and cannot be prevented by the prophy-lactic use of aspirin. This paper briefly reviews the pathogenesis of term PE and discusses strategies available for its prediction.

Keywords: PLGF; SFLT-1; aspirin; pravastatin; preeclampsia.

Publication types

  • Review

MeSH terms

  • Adult
  • Aspirin / therapeutic use*
  • Biomarkers / blood*
  • Early Diagnosis*
  • Female
  • Humans
  • Pre-Eclampsia / diagnosis*
  • Pre-Eclampsia / drug therapy*
  • Predictive Value of Tests
  • Pregnancy
  • Pregnancy Trimester, First
  • Pregnancy Trimester, Third
  • Young Adult

Substances

  • Biomarkers
  • Aspirin