Beware of the difference between randomized controlled trials and daily clinical practice (in reply to "Surgery or antibiotics for acute appendicitis? Take care about study's design and methodology!", by Ceresoli M, et al.)
Updates Surg. 2018 Dec;70(4):565-567.
doi: 10.1007/s13304-018-0540-6.
Epub 2018 May 18.
1 Department of Surgery, General, Emergency and Robotic Surgical Unit, San Francesco Hospital, Via Mannironi, 1, 08100, Nuoro, Italy. mauropodda@ymail.com.
2 Department of Surgery. II Clinica Chirurgica. Policlinico Umberto I, Sapienza University, Rome, Italy.
3 Department of Surgery, Santissima Trinità Hospital, Cagliari, Italy.