Patient involvement is essential in identifying drug-related problems

Br J Clin Pharmacol. 2018 Sep;84(9):2048-2058. doi: 10.1111/bcp.13640. Epub 2018 Jun 21.

Abstract

Aims: The aim of this study is to evaluate how critical patient involvement is in pharmacist-led clinical medication reviews and in identifying the most significant clinical drug-related problems (DRPs).

Methods: Pharmacist-led clinical medication reviews were conducted with 161 consenting patients aged ≥75 years with at least seven prescribed medicines, living independently at home in Finland. A pharmacist, a nurse and a physician evaluated the clinical significance of the DRPs identified during the patient interview at an interprofessional case conference. It was evaluated whether the most significant clinical DRPs could also have been identified through reviewing the medication list only or the medication list and certain patient details.

Results: Altogether, the 111 most significant clinical DRPs were evaluated. Only 6% could have been identified through reviewing the medication list only, and 16% through reviewing the medication list and certain patient details. Hence, 84% of the most significant clinical DRPs could only have been identified with patient involvement. The most common DRPs were: poor therapy control (25%); nonoptimal drug (22%); intentional nonadherence (12%); and additional drug needed (11%). patient involvement was critical when identifying DRPs related to additional drug needed, unintentional nonadherence, use of over-the-counter medicines or dietary supplements, or contradictions in counselling.

Conclusion: Patient involvement is essential when identifying clinical DRPs. Indeed, poor therapy control, nonoptimal drug use, intentional or unintentional nonadherence might otherwise be missed.

Keywords: drug-related problems; medication review; patient interviews; patient involvement; pharmacotherapy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Dietary Supplements / adverse effects
  • Drug Utilization Review / methods*
  • Drug Utilization Review / statistics & numerical data
  • Drug-Related Side Effects and Adverse Reactions / prevention & control*
  • Female
  • Finland
  • Humans
  • Male
  • Medication Adherence / statistics & numerical data
  • Medication Errors / prevention & control
  • Nonprescription Drugs / therapeutic use
  • Patient Participation*
  • Pharmacies / organization & administration*
  • Pharmacists / organization & administration*
  • Prescription Drugs / therapeutic use

Substances

  • Nonprescription Drugs
  • Prescription Drugs