As the incidence of osteoporosis (OP) is increasing year by year, high morbidity and mortality caused by osteoporotic fractures have become major problems of health in China and over the world. Quantitative measurement of bone using 99mTc-methylene diphosphonate ( 99mTc-MDP) provides global or local information of skeletal metabolism or transformation. In this paper, we make a brief review on the quantitative measurement of bone using 99mTc-MDP and expect to provide guidance for clinical diagnosis and treatment.
骨质疏松症（OP）发病率逐年增加，骨质疏松性骨折引发的高致残率及高致死率已成为我国乃至全球面临的重大医疗卫生问题。放射性核素 99m 锝-亚甲基二磷酸盐（ 99mTc-MDP）骨定量测定能提供全身或局部骨骼骨代谢或转化的信息。本文就放射性核素 99mTc-MDP 骨定量测定方法进行简述，以期能为临床诊疗提供参考。.
Keywords: 99mTc-methylene diphosphonate; bone turnover; osteoporosis; radionuclide bone quantitative measurement; standardized uptake value.