Severe tricuspid regurgitation due to interactions with right ventricular permanent pacemaker or defibrillator leads

Pacing Clin Electrophysiol. 2018 Jul;41(7):845-853. doi: 10.1111/pace.13369. Epub 2018 Jun 4.

Abstract

Although thought to be a rare event, permanent pacemakers and implantable cardioverter-defibrillators with right ventricular intracardiac leads have the potential to induce tricuspid valve dysfunction. Adverse lead-valve interactions can take place through a variety of mechanisms including damage at the time of implantation, leaflet pinning, or long-term fibrosis encapsulating the leaflet tissue. Clinical manifestations can display a wide range of severity, as well as a highly variable time span between implantation and hemodynamic deterioration. This review aims to describe the potential pathophysiologic effects of intracardiac device leads on the tricuspid valve, with a focus on ideal diagnostic strategies and treatment options once lead-induced valvular dysfunction is suspected.

Keywords: cardiac device; implantable cardioverter-defibrillator; pacemaker; tricuspid regurgitation; tricuspid valve; tricuspid valve repair; tricuspid valve replacement.

Publication types

  • Review

MeSH terms

  • Defibrillators, Implantable / adverse effects*
  • Heart Ventricles
  • Humans
  • Pacemaker, Artificial / adverse effects*
  • Postoperative Complications / diagnostic imaging
  • Postoperative Complications / etiology*
  • Postoperative Complications / surgery
  • Severity of Illness Index
  • Tricuspid Valve Insufficiency / diagnostic imaging
  • Tricuspid Valve Insufficiency / etiology*
  • Tricuspid Valve Insufficiency / surgery