Advances in therapies and scope for personalized medicine in Alzheimer's disease

Per Med. 2016 Mar;13(2):189-199. doi: 10.2217/pme.15.49. Epub 2016 Feb 8.

Abstract

Alzheimer's disease is one of the leading causes of death worldwide and currently does not have any cure. The rate of incidence of Alzheimer's from 2010 is up by 71%, whereas many other diseases have been decreasing in their prevalence. In this review, we have attempted to cover the current landscape of treatment alongside forthcoming advances. We have also covered the present genes identified through genome-wide association studies, which could be used as novel biomarkers and could eventually reduce the cost of treatment through early diagnosis. As this disease is highly polymorphic, applications of personalized medicine have also found its way. All these upcoming developments offer a bright hope in the diagnosis and treatment of this disease.

Keywords: Alzheimer's disease; databases; genome-wide association studies; personalized medicine; therapeutic approaches against AD.