AllergoOncology: Generating a canine anticancer IgE against the epidermal growth factor receptor

Judit Fazekas-Singer; Josef Singer; Kristina M Ilieva; Miroslawa Matz; Ina Herrmann; Edzard Spillner; Sophia N Karagiannis; Erika Jensen-Jarolim

doi:10.1016/j.jaci.2018.04.021

AllergoOncology: Generating a canine anticancer IgE against the epidermal growth factor receptor

J Allergy Clin Immunol. 2018 Sep;142(3):973-976.e11. doi: 10.1016/j.jaci.2018.04.021. Epub 2018 May 7.

Authors

Judit Fazekas-Singer¹, Josef Singer², Kristina M Ilieva³, Miroslawa Matz⁴, Ina Herrmann⁵, Edzard Spillner⁶, Sophia N Karagiannis⁷, Erika Jensen-Jarolim⁸

Affiliations

¹ Comparative Medicine, The Interuniversity Messerli Research Institute of the University of Veterinary Medicine Vienna, Medical University Vienna, University Vienna, Vienna, Austria; Institute of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
² Comparative Medicine, The Interuniversity Messerli Research Institute of the University of Veterinary Medicine Vienna, Medical University Vienna, University Vienna, Vienna, Austria; Institute of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria; Department of Internal Medicine II, University Hospital Krems, Karl Landsteiner University of Health Sciences, Krems, Austria.
³ St John's Institute of Dermatology, School of Basic & Medical Biosciences, King's College London, London, United Kingdom; NIHR Biomedical Research Centre at Guy's and St Thomas' Hospital and King's College London, Guy's Hospital, King's College London, London, United Kingdom; Breast Cancer Now Unit, School of Cancer & Pharmaceutical Sciences, King's College London, Guy's Cancer Centre, London, United Kingdom.
⁴ Institute of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
⁵ Comparative Medicine, The Interuniversity Messerli Research Institute of the University of Veterinary Medicine Vienna, Medical University Vienna, University Vienna, Vienna, Austria; Department for Companion Animals and Horses, Small Animal Clinic, Internal Medicine, University of Veterinary Medicine, Vienna, Austria.
⁶ Immunological Engineering, Department of Engineering, Aarhus University, Aarhus, Denmark.
⁷ St John's Institute of Dermatology, School of Basic & Medical Biosciences, King's College London, London, United Kingdom; NIHR Biomedical Research Centre at Guy's and St Thomas' Hospital and King's College London, Guy's Hospital, King's College London, London, United Kingdom.
⁸ Comparative Medicine, The Interuniversity Messerli Research Institute of the University of Veterinary Medicine Vienna, Medical University Vienna, University Vienna, Vienna, Austria; Institute of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria. Electronic address: erika.jensen-jarolim@meduniwien.ac.at.

PMID: 29746883
DOI: 10.1016/j.jaci.2018.04.021

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antineoplastic Agents, Immunological / pharmacology*
Cell Line
Cetuximab / pharmacology*
Cricetulus
Dogs
ErbB Receptors / genetics
ErbB Receptors / immunology*
Humans
Immunoglobulin E / immunology*
Neoplasms / drug therapy
Recombinant Proteins / immunology

Substances

Antineoplastic Agents, Immunological
Recombinant Proteins
Immunoglobulin E
ErbB Receptors
Cetuximab

Publication types

MeSH terms

Substances

Grants and funding