Pulmonary Arterial Hypertension in Women

Methodist Debakey Cardiovasc J. 2017 Oct-Dec;13(4):224-237. doi: 10.14797/mdcj-13-4-224.

Abstract

Pulmonary arterial hypertension (PAH) is characterized by pathological hemodynamic elevation in pulmonary artery pressure. Development of international registries over the last decade has raised awareness about the disease, leading to the development of new and improved therapies. Paradigm shifts such as these warrant review of existing literature regarding PAH, especially in females, as the disease continues to affect women more than males. The aim of this review is to provide an update on the classification, pathophysiology, diagnosis, and treatment of PAH while focusing specifically on its impact on women.

Keywords: hypertension; pregnancy; pulmonary artery hypertension; women.

Publication types

  • Review

MeSH terms

  • Antihypertensive Agents / adverse effects
  • Antihypertensive Agents / therapeutic use*
  • Arterial Pressure / drug effects*
  • Female
  • Health Status Disparities*
  • Healthcare Disparities*
  • Humans
  • Hypertension, Pulmonary / diagnosis
  • Hypertension, Pulmonary / drug therapy*
  • Hypertension, Pulmonary / mortality
  • Hypertension, Pulmonary / physiopathology
  • Male
  • Pulmonary Artery / drug effects*
  • Pulmonary Artery / physiopathology
  • Risk Factors
  • Sex Factors
  • Treatment Outcome
  • Women's Health*

Substances

  • Antihypertensive Agents