Anaphylactic shock perioperative to patent blue dye

BMJ Case Rep. 2018 May 7:2018:bcr2018224330. doi: 10.1136/bcr-2018-224330.

Abstract

Patent blue is one of the most used dyes for the identification of sentinel lymph nodes in breast cancer. This report describes a case of an anaphylactic shock reaction to patent blue dye in a patient with cross-reactivity to methylene blue. Therefore, after allergy confirmation, the operation was repeated avoiding blue dye and an alternative labelling technique with 99mTc albumin nanocolloids was used.

Keywords: anaesthesia; healthcare improvement and patient safety; immunology; intensive care; medical management.

Publication types

  • Case Reports

MeSH terms

  • Anaphylaxis / chemically induced*
  • Breast Neoplasms / pathology
  • Breast Neoplasms / surgery*
  • Carcinoma, Intraductal, Noninfiltrating / pathology
  • Carcinoma, Intraductal, Noninfiltrating / surgery*
  • Coloring Agents / adverse effects
  • Diagnosis, Differential
  • Female
  • Humans
  • Lymph Nodes / pathology
  • Lymph Nodes / surgery*
  • Mastectomy / methods
  • Middle Aged
  • Perioperative Period / adverse effects*
  • Perioperative Period / methods
  • Rosaniline Dyes / administration & dosage
  • Rosaniline Dyes / adverse effects*
  • Sentinel Lymph Node Biopsy / adverse effects
  • Sentinel Lymph Node Biopsy / methods*
  • Skin Tests / methods
  • Treatment Outcome

Substances

  • Coloring Agents
  • Rosaniline Dyes
  • sulfan blue