Anatomy, Physiology, and Clinical Syndromes of the Basal Ganglia: A Brief Review

Semin Pediatr Neurol. 2018 Apr:25:2-9. doi: 10.1016/j.spen.2017.12.005. Epub 2017 Dec 27.

Abstract

Movement disorders typically arise from dysfunction of the basal ganglia (BG), cerebellum, or both. The BG-a group of deep, subcortical structures-form complex circuits that shape motor control and motor learning, as well as limbic and associative functions. In this article, we summarize the anatomy and physiology of the BG and cerebellum, and briefly highlight the clinical syndromes that may arise in the context of their injury or dysfunction.

Publication types

  • Review

MeSH terms

  • Animals
  • Basal Ganglia / anatomy & histology
  • Basal Ganglia / pathology*
  • Basal Ganglia / physiology
  • Basal Ganglia / physiopathology*
  • Humans
  • Movement Disorders / pathology*
  • Movement Disorders / physiopathology*
  • Neural Pathways / anatomy & histology
  • Neural Pathways / pathology
  • Neural Pathways / physiology
  • Neural Pathways / physiopathology
  • Syndrome