Endoscopic Follow-up of Intestinal Transplant Recipients

Gastroenterol Clin North Am. 2018 Jun;47(2):381-391. doi: 10.1016/j.gtc.2018.01.012.

Abstract

The growing population of intestinal transplant recipients present a unique challenge to the gastroenterologists responsible for their support and evaluation. Improvements in patient and graft survival are largely attributed to surgical advancements, refined antirejection therapy, and enhanced endoscopic surveillance protocols that better perceive rejection and other complications. This article reviews the endoscopic management and interventions provided for transplant recipients at the University of Illinois Hospital with complications, such as acute rejection, ischemia, bleeding, fistula, post-transplant lymphoproliferative disorder, and gastroparesis. Further research is needed on promising strategies currently used for related diseases to treat and sustain the intestinal graft.

Keywords: Acute rejection; Intestinal transplant complications; Intestine transplant; Magnification endoscopy; Post-transplant lymphoproliferative disorder; Research directions in intestine transplants; Twin transplants.

Publication types

  • Review

MeSH terms

  • Aftercare
  • Biopsy
  • Endoscopy, Gastrointestinal*
  • Gastrointestinal Hemorrhage / diagnostic imaging*
  • Gastrointestinal Hemorrhage / therapy
  • Gastroparesis / etiology
  • Graft Rejection / diagnosis*
  • Graft Rejection / drug therapy
  • Humans
  • Intestinal Mucosa / pathology*
  • Intestines / blood supply
  • Intestines / transplantation*
  • Ischemia / diagnostic imaging
  • Postoperative Complications / diagnosis*
  • Postoperative Complications / etiology
  • Postoperative Complications / therapy