Isocyanate-Based Dendritic Building Blocks: Combinatorial Tier Construction and Macromolecular-Property Modification

George R Newkome; Claus D Weis; Charles N Moorefield; Gregory R Baker; Bradley J Childs; Jon Epperson

doi:10.1002/(SICI)1521-3773(19980216)37:3<307::AID-ANIE307>3.0.CO;2-L

Isocyanate-Based Dendritic Building Blocks: Combinatorial Tier Construction and Macromolecular-Property Modification

Angew Chem Int Ed Engl. 1998 Feb 16;37(3):307-310. doi: 10.1002/(SICI)1521-3773(19980216)37:3<307::AID-ANIE307>3.0.CO;2-L.

Authors

George R Newkome¹, Claus D Weis¹, Charles N Moorefield¹, Gregory R Baker¹, Bradley J Childs¹, Jon Epperson¹

Affiliation

¹ Center for Molecular Design and Recognition, Department of Chemistry, University of South Florida, 4202 East Fowler Avenue, Tampa, FL 33620-5250 (USA), Fax: Int. code+(1) 813 974-4962.

PMID: 29711250
DOI: 10.1002/(SICI)1521-3773(19980216)37:3<307::AID-ANIE307>3.0.CO;2-L

Abstract

Used individually or combinatorially, unique isocyanate-based dendritic monomers generate homo- and heterofunctional materials (the sketch shows schematically a molecule with a heterofunctional surface). Tier construction by combinatorial monomer addition offers new avenues to macromolecular architectural design and the control of physical properties.

Keywords: Combinatorial synthesis; Dendrimers; Isocyanates.