Estrus Suppression in Dogs

Vet Clin North Am Small Anim Pract. 2018 Jul;48(4):595-603. doi: 10.1016/j.cvsm.2018.04.001. Epub 2018 Apr 27.

Abstract

Since 1952, scientists have studied estrus suppression in dogs. Estrus suppression in dogs must be safe and reliable. Medications used for estrus suppression in bitches include gonadotropin-releasing hormone (GnRH) agonists, GnRH antagonists, progestogens, and androgens. Despite widespread availability of these medications throughout the rest of the world, there are no drugs currently labeled for canine estrus induction in the United States.

Keywords: Agonist; Androgen; Antagonist; GnRH; Hormonal downregulation; Progestogen.

Publication types

  • Review

MeSH terms

  • Animals
  • Dogs
  • Estrus / drug effects*
  • Estrus / physiology
  • Female
  • Gonadotropin-Releasing Hormone / antagonists & inhibitors
  • Gonadotropin-Releasing Hormone / pharmacology*
  • Progesterone / blood

Substances

  • Gonadotropin-Releasing Hormone
  • Progesterone