Transvenous phrenic nerve stimulation, a novel therapeutic approach for central sleep apnea

Ning Ding; Xilong Zhang

doi:10.21037/jtd.2018.03.59

Transvenous phrenic nerve stimulation, a novel therapeutic approach for central sleep apnea

J Thorac Dis. 2018 Mar;10(3):2005-2010. doi: 10.21037/jtd.2018.03.59.

Authors

Ning Ding¹, Xilong Zhang¹

Affiliation

¹ Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.

Abstract

Central sleep apnea (CSA) is common in heart failure (HF) patients. Traditional treatment of CSA, including continuous positive airway pressure (CPAP), adaptive servo ventilation (ASV), oxygen therapy, and CO₂ inhalation, has respective limitations. Transvenous phrenic nerve stimulation (PNS), a novel therapeutic approach for CSA, was proved to be effective and safe. The remedē^® system and related transvenous PNS methods was approved by FDA in 2017, for treating moderate to severe CSA.

Keywords: Central sleep apnea (CSA); phrenic nerve stimulation; remedē® system.

Publication types

Review