Measuring Vaccine Responses in the Multiplex Era

Methods Mol Biol. 2018:1781:327-340. doi: 10.1007/978-1-4939-7828-1_17.

Abstract

Vaccine studies in psychoneuroimmunology (PNI) provide an insight into biopsychosocial interactions and their role in infectious diseases. How to measure vaccine responses is therefore of critical importance for PNI researchers. In this chapter, traditional and modern immunoassays for the assessment of vaccine responses are discussed, highlighting how modern multiplex techniques provide researchers with greater capacity and opportunity for novel research relating to vaccine outcomes.

Keywords: ELISA; Immunoassay; Microarray; Multiplex; Vaccination.

MeSH terms

  • Biomarkers / analysis
  • Enzyme-Linked Immunosorbent Assay / methods*
  • Humans
  • Immunoglobulin G / analysis
  • Influenza, Human / immunology*
  • Influenza, Human / prevention & control
  • Influenza, Human / psychology
  • Microarray Analysis / methods*
  • Psychoneuroimmunology / methods*
  • Vaccines / immunology*

Substances

  • Biomarkers
  • Immunoglobulin G
  • Vaccines