A New Approach to an Old Problem: One Brave Idea

Circ Res. 2018 Apr 27;122(9):1172-1175. doi: 10.1161/CIRCRESAHA.118.310941.

Authors

James Cranley^{1

2}, Calum A MacRae³

Affiliations

¹ From the Department of Medicine, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, United Kingdom (J.C.).
² Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (J.C., C.A.M.).
³ Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (J.C., C.A.M.). cmacrae@bwh.harvard.edu.

PMID: 29700065
DOI: 10.1161/CIRCRESAHA.118.310941

No abstract available

Keywords: arteriosclerosis; hypercholesterolemia; incidence; male; risk factors.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Academies and Institutes / organization & administration*
American Heart Association
Anticholesteremic Agents / therapeutic use
Atherosclerosis / complications
Atherosclerosis / genetics
Causality
Coronary Disease / epidemiology
Coronary Disease / etiology*
Coronary Disease / genetics
Coronary Disease / prevention & control
Drug Industry
Dyslipidemias / complications
Dyslipidemias / drug therapy
Dyslipidemias / genetics
Gene-Environment Interaction
Genetic Predisposition to Disease
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use
Intersectoral Collaboration
Lipoproteins, LDL / genetics
Lipoproteins, LDL / physiology
Models, Cardiovascular
Phenotype
United States
Wnt Signaling Pathway

Substances

Anticholesteremic Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lipoproteins, LDL