A Proteomic Connectivity Map

Christian Feller; Ruedi Aebersold

doi:10.1016/j.cels.2018.04.007

A Proteomic Connectivity Map

Cell Syst. 2018 Apr 25;6(4):403-405. doi: 10.1016/j.cels.2018.04.007.

Authors

Christian Feller¹, Ruedi Aebersold²

Affiliations

¹ Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland. Electronic address: feller@imsb.biol.ethz.ch.
² Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland; Faculty of Science, University of Zurich, Switzerland. Electronic address: aebersold@imsb.biol.ethz.ch.

PMID: 29698646
DOI: 10.1016/j.cels.2018.04.007

Abstract

Litichevskiy et al. describe the first large-scale use of targeted mass spectrometry to systematically investigate phospho-protein and histone modification networks across a panel of cell lines subjected to drug perturbations.

Publication types

Comment

MeSH terms

Chromatin*
Gene Library
Mass Spectrometry
Protein Processing, Post-Translational
Proteomics*

Substances

Chromatin