PIP: Post-coital contraception or rather interception, a term suggested here since it is non-preventive, per definition is applied after the hypothetical time of contraception. Various methods have been proposed for "day after" interventions among which the administration of estro-progestins are the simplest, least expensive and least likely to cause serious side effects. In order to reduce side effects, a trial involving 35 women was conducted at the hospital in Avigliana. A biphasic combination of .150 mg desogestrel + .030 mg ethinyl estradiol was administered in the form of 2 pills within a period of 12 hours or 24 hours after intercourse. 6 tables display age, educational level, occupation, motive, day during menstrual cycle, time after intercourse that treatment was begun. 65.7% of the women were less than 30, 8% less than 20 years old. Almost 80% were treated during their mid-cycles, where the chance of becoming pregnant is greatest, i.e., 20%. Not one pregnancy was observed. It is impossible to ascertain how many conceptions actually did occur due to the nonexistence of methods for determining avoided pregnancies. The only side effects reported were nausea and vomiting of short duration. Menstruation reoccurred within 21 days of treatment for 98%. A small possibility of ectopic pregnancy, however, does exist. Fetal damage from the steroids seems excludable, due to the extremely early period of administration. An increased demand for post-coital interception has been registered for the youngest users, especially among students and employees, which indicate a high or medium high level of education, but it is probably also due to erratic, occasional and inexperienced sexual behavioral patterns, and a lack of knowledge concerning the choice of the right kind of contraception.