Lymphoepithelioma-like carcinoma of the uterine cervix: a case report

Eur J Gynaecol Oncol. 2017;38(3):459-461.

Abstract

Lymphoepithelioma-like carcinoma (LELC) is a rare variant of carcinoma of the uterine cervix, of which Epstein-Barr virus (EBV) and/or human papilloma virus (HPV) may play an important role in the pathogenesis. The authors report a case of a patient with cervical LELC who was also examined for the presence of EBV and HPV. A 31-year-old Japanese female presented with irregular genital bleeding. The biopsy showed an invasive squamous cell carcinoma. Based on the clinical data, the patient was diagnosed as having squamous cervical carcinoma, and radical hysterectomy with ovarian conservation was performed. A diagnosis of cervical LELC was then made by histological methods. An additional examination revealed that the patient was infected with HPV types 16 and 71, but not infected with EBV.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Carcinoma / diagnosis
  • Carcinoma / virology*
  • Female
  • Herpesvirus 4, Human / isolation & purification
  • Humans
  • Papillomaviridae / isolation & purification*
  • Uterine Cervical Neoplasms / diagnosis
  • Uterine Cervical Neoplasms / virology*