Successful Treatment of Cerebral Toxoplasmosis Using Pyrimethamine Oral Solution Compounded From Inexpensive Bulk Powder

Open Forum Infect Dis. 2018 Apr 18;5(4):ofy055. doi: 10.1093/ofid/ofy055. eCollection 2018 Apr.

Abstract

A price increase of pyrimethamine tablets in the United States has made the life-saving drug difficult to acquire for hospitalized patients who need it most. We report the successful use of a pyrimethamine oral suspension compounded from an economical bulk powder in a patient with acute toxoplasmic encephalitis.

Keywords: Toxoplasma gondii; bulk powder; encephalitis; oral suspension; pyrimethamine.