Duodenoscopy: an amplifier of cross-transmission during a carbapenemase-producing Enterobacteriaceae outbreak in a gastroenterology pathway

C Bourigault; F Le Gallou; N Bodet; N Musquer; M-E Juvin; S Corvec; N Ferronnière; S Wiesel; J Gournay; G Birgand; M Le Rhun; D Lepelletier

doi:10.1016/j.jhin.2018.04.015

Duodenoscopy: an amplifier of cross-transmission during a carbapenemase-producing Enterobacteriaceae outbreak in a gastroenterology pathway

J Hosp Infect. 2018 Aug;99(4):422-426. doi: 10.1016/j.jhin.2018.04.015. Epub 2018 Apr 21.

Authors

C Bourigault¹, F Le Gallou², N Bodet³, N Musquer⁴, M-E Juvin², S Corvec², N Ferronnière², S Wiesel², J Gournay⁵, G Birgand⁶, M Le Rhun⁴, D Lepelletier³

Affiliations

¹ Bacteriology and Hygiene Department, Nantes University Hospital, Nantes, France. Electronic address: celine.bourigault@chu-nantes.fr.
² Bacteriology and Hygiene Department, Nantes University Hospital, Nantes, France.
³ Bacteriology and Hygiene Department, Nantes University Hospital, Nantes, France; Endoscope Reprocessing Unit (CeTrES), Nantes University Hospital, Nantes, France.
⁴ Digestive Endoscopy Department, Nantes University Hospital, Nantes, France.
⁵ Gastroenterology Department, Nantes University Hospital, Nantes, France.
⁶ Regional Center for Infection Prevention and Control, Nantes, France.

PMID: 29684421
DOI: 10.1016/j.jhin.2018.04.015

Abstract

Carbapenemase-producing Klebsiella pneumoniae (OXA-48 CPE) were identified in five patients who underwent an endoscopy with the same duodenoscope in October 2015. The endoscope was the only epidemiological link between these cases. A transient contamination of the duodenoscope following a failure in the disinfection process may have been the cause of transmission.

Keywords: Carbapenemase-producing Enterobacteriaceae; Duodenoscopy; Outbreak; Reprocessing.

MeSH terms

Adult
Aged
Aged, 80 and over
Carbapenem-Resistant Enterobacteriaceae / isolation & purification*
Disease Outbreaks*
Disease Transmission, Infectious*
Duodenoscopy / adverse effects*
Female
Gastrointestinal Diseases / diagnosis
Humans
Klebsiella Infections / epidemiology*
Klebsiella Infections / microbiology
Klebsiella Infections / transmission*
Klebsiella pneumoniae / isolation & purification*
Male