Does induction of labour in nulliparous hypertensive women result in vaginal birth? - A descriptive study utilising birth registry data

Pregnancy Hypertens. 2018 Apr:12:16-22. doi: 10.1016/j.preghy.2018.01.010. Epub 2018 Jan 31.

Abstract

Background: Induction of labour (IOL) is a common procedure yet we have little information on the efficacy of the process for women with a hypertensive disorder of pregnancy (HDP).

Objective: To describe the birth type and associated factors in nulliparous HDP women undergoing an induction of labour.

Study design: Statutorily collected datasets on every birth and hospital admission which occurred in the state of NSW Australia between the years 2000-2011 were analysed. Hypertensive women were compared to normotensive women.

Results: Of the nulliparous women, 9.9% had a HDP. IOL for HDP women were 56.2% in a cohort of 447 558 women. The AOR for a woman with a HDP undergoing an IOL resulting in a vaginal delivery when compared to a normotensive woman is 0.86 (95% CI 0.83-0.88). Prior to 33 weeks, the lowest perinatal mortality rates (PMR) are seen in women who undergo elective caesarean section (C/S). For women with preeclampsia (PE), lower PMR are seen in women who undergo IOL.

Conclusion: For women with PE and SPE, IOL resulted in lower rates of vaginal delivery than spontaneous labour when compared to normotensive women who also underwent IOL. Women with PE at ≥33 weeks who underwent IOL had the lowest PMR.

Keywords: Chronic hypertension; Gestational hypertension; Induction of labour; Preeclampsia; Pregnancy hypertension.

Publication types

  • Review

MeSH terms

  • Adult
  • Blood Pressure*
  • Case-Control Studies
  • Cesarean Section
  • Female
  • Humans
  • Hypertension, Pregnancy-Induced / diagnosis
  • Hypertension, Pregnancy-Induced / mortality
  • Hypertension, Pregnancy-Induced / physiopathology*
  • Infant, Newborn
  • Labor, Induced* / adverse effects
  • Labor, Induced* / mortality
  • Labor, Obstetric*
  • Maternal Mortality
  • New South Wales / epidemiology
  • Parity*
  • Perinatal Mortality
  • Pregnancy
  • Registries
  • Risk Factors
  • Treatment Outcome
  • Young Adult