Effective norm emergence in cell systems under limited communication

BMC Bioinformatics. 2018 Apr 11;19(Suppl 5):119. doi: 10.1186/s12859-018-2097-2.

Abstract

Background: The cooperation of cells in biological systems is similar to that of agents in cooperative multi-agent systems. Research findings in multi-agent systems literature can provide valuable inspirations to biological research. The well-coordinated states in cell systems can be viewed as desirable social norms in cooperative multi-agent systems. One important research question is how a norm can rapidly emerge with limited communication resources.

Results: In this work, we propose a learning approach which can trade off the agents' performance of coordinating on a consistent norm and the communication cost involved. During the learning process, the agents can dynamically adjust their coordination set according to their own observations and pick out the most crucial agents to coordinate with. In this way, our method significantly reduces the coordination dependence among agents.

Conclusion: The experiment results show that our method can efficiently facilitate the social norm emergence among agents, and also scale well to large-scale populations.

Keywords: Cell system; Cooperative multi-agent system; Limited communication; Reinforcement learning; Social norms.

MeSH terms

  • Algorithms
  • Cell Communication*
  • Cells / metabolism*
  • Humans
  • Models, Biological