Long-term follow-up in patients treated by stent implantation for post-ablation pulmonary vein stenosis

J Interv Card Electrophysiol. 2018 Dec;53(3):309-315. doi: 10.1007/s10840-018-0370-y. Epub 2018 Apr 18.

Abstract

Purpose: Symptomatic severe pulmonary vein stenosis (PVS) after catheter ablation of atrial fibrillation (AF) is a rare but well-recognized complication. Treatment options include pulmonary vein angioplasty with or without drug eluting balloons or angioplasty with stent implantation. The treatment of choice is unclear. In our center, pulmonary vein stenting is the treatment of choice for significantly stenotic veins. We present the long-term clinical outcome of 9 patients treated with stent implantation.

Methods: Between 2001 and 2015, 3048 patients with AF were treated with catheter ablation at our institution, of which 9 developed symptomatic PVS. A total of 11 PVS were treated. Pre-procedural imaging (CT, MR, transesophageal echocardiography, angiography) was performed in all patients.

Results: Mean time from ablation to stenting was 18 months. Three patients had recurrent pneumonia and the remaining reduced functional capacity (NYHA 2). All patients were in functional capacity NYHA 1 (p < 0.05) after a mean follow-up of 64 (18-132) months. Three patients still had paroxysmal AF, of which two have undergone repeated ablation.

Conclusions: Symptomatic PVS after AF ablation can be successfully treated by stent implantation with durable results and good clinical outcome. AF ablation is still a feasible option after stent deployment.

Keywords: Ablation; Atrial fibrillation; Long-term follow-up; Pulmonary vein stenosis; Stent implantation.

MeSH terms

  • Aged
  • Angiography / methods
  • Atrial Fibrillation / epidemiology
  • Atrial Fibrillation / surgery*
  • Blood Vessel Prosthesis Implantation* / instrumentation
  • Blood Vessel Prosthesis Implantation* / methods
  • Catheter Ablation / adverse effects*
  • Catheter Ablation / methods
  • Echocardiography, Transesophageal / methods
  • Female
  • Humans
  • Long Term Adverse Effects* / diagnosis
  • Long Term Adverse Effects* / surgery
  • Male
  • Middle Aged
  • Norway / epidemiology
  • Outcome Assessment, Health Care
  • Postoperative Complications* / diagnosis
  • Postoperative Complications* / surgery
  • Pulmonary Veins / diagnostic imaging
  • Pulmonary Veins / surgery
  • Retrospective Studies
  • Stenosis, Pulmonary Vein* / diagnosis
  • Stenosis, Pulmonary Vein* / etiology
  • Stenosis, Pulmonary Vein* / surgery