Hydroxychloroquine-induced hypoglycaemia in non-diabetic renal patient on peritoneal dialysis

BMJ Case Rep. 2018 Apr 18:2018:bcr2017223639. doi: 10.1136/bcr-2017-223639.

Abstract

Hydroxychloroquine (HCQ) is a commonly used drug for the treatment of systemic lupus erythematosus (SLE). Renal involvement is common in SLE. We present a 25-year-old woman with lupus nephritis on peritoneal dialysis whose lupus was quite silent for almost three years, and secondary to HCQ she developed severe hypoglycaemic episodes, which were completely resolved after stopping HCQ.

Keywords: dialysis; drugs: musculoskeletal and joint diseases; renal system; systemic lupus erythematosus; unwanted effects/adverse reactions.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Antirheumatic Agents / administration & dosage
  • Antirheumatic Agents / adverse effects*
  • Female
  • Humans
  • Hydroxychloroquine / administration & dosage
  • Hydroxychloroquine / adverse effects*
  • Hypoglycemia / chemically induced*
  • Lupus Nephritis / blood
  • Lupus Nephritis / drug therapy*
  • Lupus Nephritis / physiopathology
  • Peritoneal Dialysis*
  • Treatment Outcome

Substances

  • Antirheumatic Agents
  • Hydroxychloroquine