Vibralactones U-W, three vibralactone derivatives from cultures of the basidiomycete Boreostereum vibrans

J Asian Nat Prod Res. 2019 Jul;21(7):603-609. doi: 10.1080/10286020.2018.1461844. Epub 2018 Apr 18.

Abstract

Three new vibralactone derivatives, namely vibralactones U-W (1-3), together with vibralactone (4), have been isolated from cultures of the basidiomycete Boreostereum vibrans. Their structures were determined on the basis of spectroscopic methods and literature data. All compounds showed no activities to five human cancer cell lines.

Keywords: Boreostereaceae; structural elucidation; vibralactone derivatives.

MeSH terms

  • Antibiotics, Antineoplastic / chemistry*
  • Antibiotics, Antineoplastic / pharmacology*
  • Basidiomycota / chemistry*
  • Cell Line, Tumor
  • Drug Screening Assays, Antitumor
  • Humans
  • Lactones / chemistry*
  • Lactones / pharmacology*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular

Substances

  • Antibiotics, Antineoplastic
  • Lactones
  • vibralactone