Electrospun Fibers for Cartilage Tissue Regeneration

Abstract

Background: Cartilage injury has always been puzzled for clinicians. The treatments used clinically for cartilage injury usually bring about fibrocartilage. The emergence of tissue engineering lights up the hope of cartilage repair.

Objective: This review will sum up the existing learnings about electrospun fibers, revolving about the electrospinning materials, micromorphology, improvements and electrospun technologies newly developed in cartilage repair and regeneration.

Results: Electrospun fibers as scaffolds for cartilage regeneration have been one of researching hotspots for years. The studies about new electrospun materials and new electrospinning technologies greatly promoted the development of this field.

Conclusion: Electrospun fibers have showed great potential in cartilage regeneration. But there is still a long way to go before clinical application. The material embellishment and structure imitation should be highlighted in future.

Keywords: Electrospun; biomaterials; cartilage; electrospinning materials; stem cell; tissue engineering..