[Cesarean after labor induction: Risk factors and prediction score]

Gynecol Obstet Fertil Senol. 2018 May;46(5):458-465. doi: 10.1016/j.gofs.2018.03.008. Epub 2018 Apr 12.
[Article in French]

Abstract

Objectives: The objective of the study is to determine the risk factors for caesarean section at the time of labor induction, to establish a prediction algorithm, to evaluate its relevance and to compare the results with observation.

Methods: A retrospective study was carried out over a year at Nantes University Hospital with 941 cervical ripening and labor inductions (24.1%) terminated by 167 caesarean sections (17.8%). Within the cohort, a case-control study was conducted with 147 caesarean sections and 148 vaginal deliveries. A multivariate analysis was carried out with a logistic regression allowing the elaboration of an equation of prediction and an ROC curve and the confrontation between the prediction and the reality.

Results: In univariate analysis, six variables were significant: nulliparity, small size of the mother, history of scarried uterus, use of prostaglandins as a mode of induction, unfavorable Bishop score<6, variety of posterior release. In multivariate analysis, five variables were significant: nulliparity, maternal size, maternal BMI, scar uterus and Bishop score. The most predictive model corresponded to an area under the curve of 0.86 (0.82-0.90) with a correct prediction percentage ("well classified") of 67.6% for a caesarean section risk of 80%.

Conclusion: The prediction criteria would make it possible to inform the woman and the couple about the potential risk of Caesarean section in urgency or to favor a planned Caesarean section or a low-lying attempt on more objective, repeatable and transposable arguments in a medical team.

Keywords: Algorithm; Algorithme; Bishop; Caeserean; Césarienne; Déclenchement; Labor induction; Prediction; Prédiction.

MeSH terms

  • Adolescent
  • Adult
  • Body Mass Index
  • Body Size
  • Case-Control Studies
  • Cervical Ripening
  • Cesarean Section* / statistics & numerical data
  • Cicatrix
  • Female
  • Hospitals, University
  • Humans
  • Labor, Induced* / adverse effects
  • Labor, Induced* / methods
  • Parity
  • Pregnancy
  • Prostaglandins / administration & dosage
  • Prostaglandins / adverse effects
  • Retrospective Studies
  • Risk Factors
  • Uterus / pathology

Substances

  • Prostaglandins