Synthetic gene drive: between continuity and novelty: Crucial differences between gene drive and genetically modified organisms require an adapted risk assessment for their use

Samson Simon; Mathias Otto; Margret Engelhard

doi:10.15252/embr.201845760

Synthetic gene drive: between continuity and novelty: Crucial differences between gene drive and genetically modified organisms require an adapted risk assessment for their use

EMBO Rep. 2018 May;19(5):e45760. doi: 10.15252/embr.201845760. Epub 2018 Apr 12.

Authors

Samson Simon¹, Mathias Otto¹, Margret Engelhard¹

Affiliation

¹ Federal Agency for Nature Conservation (BfN), Division II.3.3, Assessment of Genetically Modified Organisms Genetic Engineering Act, Bonn, Germany.

Abstract

Gene drive organisms differ from “classical” genetically modified organisms in several crucial aspects. It would require new approaches for risk assessment to gauge their potential impact on the environment.

MeSH terms

Animals
CRISPR-Cas Systems
Gene Drive Technology*
Genes, Synthetic*
Organisms, Genetically Modified*
Plants, Genetically Modified / adverse effects
Plants, Genetically Modified / genetics
Risk Assessment