The status quo and challenges of genetic diagnosis in children with steroid-resistant nephrotic syndrome

World J Pediatr. 2018 Apr;14(2):105-109. doi: 10.1007/s12519-018-0156-4. Epub 2018 Apr 11.

Authors

Yan-Yan Jin¹, Bing-Yu Feng^{1

2}, Jian-Hua Mao³

Affiliations

¹ Department of Nephrology, Children's Hospital, Zhejiang University School of Medicine, #57 Zhugan Lane, Hangzhou, 310003, China.
² Department of Paediatrics, The First People's Hospital of Huzhou, Huzhou, 313000, China.
³ Department of Nephrology, Children's Hospital, Zhejiang University School of Medicine, #57 Zhugan Lane, Hangzhou, 310003, China. maojh88@zju.edu.cn.

PMID: 29644498
DOI: 10.1007/s12519-018-0156-4

No abstract available

Publication types

Editorial
Review

MeSH terms

Adrenal Cortex Hormones / therapeutic use*
Age Factors
Child
Child, Preschool
Disease Progression
Drug Resistance*
Female
Genetic Predisposition to Disease / epidemiology*
Genetic Testing / methods
Glomerular Filtration Rate / physiology
Humans
Incidence
Intracellular Signaling Peptides and Proteins / genetics
Kidney Function Tests
Male
Membrane Proteins / genetics
Nephrotic Syndrome / diagnosis*
Nephrotic Syndrome / drug therapy
Nephrotic Syndrome / epidemiology
Nephrotic Syndrome / genetics*
Prognosis
Protein Kinases / genetics
Risk Assessment
Severity of Illness Index
Sex Factors
Suppressor of Cytokine Signaling 3 Protein / genetics

Substances

Adrenal Cortex Hormones
Intracellular Signaling Peptides and Proteins
Membrane Proteins
NPHS2 protein
SOCS3 protein, human
Suppressor of Cytokine Signaling 3 Protein
COQ8B protein, human
Protein Kinases