The ORBITA trial: A point of view

Rev Assoc Med Bras (1992). 2018 Feb;64(2):100-103. doi: 10.1590/1806-9282.64.02.100.

Abstract

Treatment of stable coronary artery disease (CAD) relies on improved prognosis and relief of symptoms. National and international guidelines on CAD support the indication for revascularization in patients with limiting symptoms and refractory to drug treatment. Previous studies attested the efficacy of angioplasty to improve angina as well as the functional capacity of patients with symptomatic stable CAD. The ORBITA trial, recently published in an international journal, showed no benefit in terms of exercise tolerance compared to a placebo procedure in a population of single-vessel patients undergoing contemporary percutaneous coronary intervention. In this point of view article, the authors discuss the ORBITA trial regarding methodological issues, limitations and clinical applicability.

Publication types

  • Comment

MeSH terms

  • Angina, Stable / surgery*
  • Coronary Artery Disease*
  • Double-Blind Method
  • Humans
  • Percutaneous Coronary Intervention*
  • Prognosis