Dispersion of multi-walled carbon nanotubes in [BMIM]PF6 for electrochemical sensing of acetaminophen

Rayane N Gomes; Camila P Sousa; Paulo N S Casciano; Francisco Wirley P Ribeiro; Simone Morais; Pedro de Lima-Neto; Adriana N Correia

doi:10.1016/j.msec.2018.03.016

Dispersion of multi-walled carbon nanotubes in [BMIM]PF₆ for electrochemical sensing of acetaminophen

Mater Sci Eng C Mater Biol Appl. 2018 Jul 1:88:148-156. doi: 10.1016/j.msec.2018.03.016. Epub 2018 Mar 20.

Authors

Rayane N Gomes¹, Camila P Sousa¹, Paulo N S Casciano¹, Francisco Wirley P Ribeiro², Simone Morais³, Pedro de Lima-Neto¹, Adriana N Correia¹

Affiliations

¹ Departamento de Química Analítica e Físico-Química, Centro de Ciências, Universidade Federal do Ceará, Bloco 940, Campus do Pici, 60440-900 Fortaleza, CE, Brazil.
² Instituto de Formação de Educadores, Universidade Federal do Cariri, Rua Olegário Emídio de Araújo, S/N, Brejo Santo, 63260-970 Brejo Santo, CE, Brazil. Electronic address: wirley.ribeiro@ufca.edu.br.
³ REQUIMTE-LAQV, Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, Rua Dr. Bernardino de Almeida 431, 4200-072 Porto, Portugal.

PMID: 29636130
DOI: 10.1016/j.msec.2018.03.016

Abstract

The influence of functionalized multi-walled carbon nanotubes (fMWCNT) in the presence of 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM]PF₆) in different ratios was investigated on the acetaminophen (ACOP) electrochemical determination. The electrochemical behavior of the ACOP exhibited a pair of well-defined redox peaks, suggesting that the reversibility of ACOP was significantly improved in comparison to irreversible oxidation peak on bare GCE. The redox process was controlled by adsorption, involves two electrons and the value of apparent rate constant (k_s) was equal to 14.7 s^-1 ± 3.6 s^-1. The analytical curves were obtained for concentrations of ACOP ranging from 0.3 to 3.0 μmol L^-1. The values of the detection limit were calculated from SWV and found to be 6.73 × 10^-8 mol L^-1. The proposed electrochemical sensor exhibited good stability and reproducibility and was applied for ACOP determination in tablets (Tylenol® and Tylenol®DC) with satisfactory results.

Keywords: 1-Butyl-3-methylimidazolium hexafluorophosphate; Electrochemical sensor; Paracetamol; Square-wave voltammetry; fMWCNT.

MeSH terms

Acetaminophen / analysis*
Electrochemical Techniques / methods*
Imidazoles / chemistry*
Nanotubes, Carbon / chemistry*

Substances

1-butyl-3-methylimidazolium hexafluorophosphate
Imidazoles
Nanotubes, Carbon
Acetaminophen