Porcine-like G3P[6] and G4P[6] rotavirus A strains detected from children with diarrhoea in Vietnam

Arch Virol. 2018 Aug;163(8):2261-2263. doi: 10.1007/s00705-018-3836-4. Epub 2018 Apr 5.

Abstract

Animal rotavirus A (RVA) strains can infect children and cause diarrhoea. We determined the full genome sequences of one G3P[6] strain (NT0001) and five G4P[6] strains (NT0042, NT0077, NT0205, NT0599, and NT0621) detected from children with diarrhoea in Vietnam in 2007-2008. Strain NT0001 had a genotype constellation of: G3-P[6]-I5-R1-C1-M1-A8-N1-T1-E1-H1, strain NT0042: G4-P[6]-I1-R1-C1-M1-A8-N1-T1-E1-H1, strain NT0077: G4-P[6]-I5-R1-C1-M1-A8-N1-T7-E1-H1, and strains NT0205, NT0599, and NT0621: G4-P[6]-I1-R1-C1-M1-A1-N1-T1-E1-H1. Sequence divergence data and phylogenetic analysis showed that they were different porcine RVA strains that independently and directly crossed the host species barrier to infect children.

MeSH terms

  • Animals
  • Diarrhea / virology*
  • Feces / virology
  • Female
  • Genome, Viral
  • Genotype
  • Humans
  • Infant
  • Male
  • Phylogeny
  • Rotavirus / classification
  • Rotavirus / genetics
  • Rotavirus / isolation & purification*
  • Rotavirus Infections / veterinary*
  • Rotavirus Infections / virology*
  • Swine
  • Swine Diseases / virology*
  • Vietnam
  • Viral Proteins / genetics

Substances

  • Viral Proteins