Abstract
Dolutegravir is an increasingly-used second-generation human immunodeficiency virus integrase strand transfer inhibitor. Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome has been described in several patients treated with raltegravir but to our knowledge, there is no previous report of DRESS syndrome associated with dolutegravir.
Keywords:
Antiretroviral therapy; dolutegravir; human immunodeficiency virus; toxicity.
MeSH terms
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Anti-HIV Agents / administration & dosage
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Anti-HIV Agents / adverse effects*
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Antiretroviral Therapy, Highly Active
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Drug Hypersensitivity Syndrome / diagnosis*
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Drug Interactions
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Eosinophilia / chemically induced*
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Exanthema / chemically induced*
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Fatal Outcome
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HIV Integrase Inhibitors / administration & dosage
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HIV Integrase Inhibitors / adverse effects*
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Heterocyclic Compounds, 3-Ring / administration & dosage
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Heterocyclic Compounds, 3-Ring / adverse effects*
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Humans
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Male
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Middle Aged
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Oxazines
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Piperazines
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Pyridones
Substances
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Anti-HIV Agents
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HIV Integrase Inhibitors
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Heterocyclic Compounds, 3-Ring
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Oxazines
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Piperazines
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Pyridones
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dolutegravir