[Evaluation of living kidney donors renal function]

François Gaillard; Marie Courbebaisse

doi:10.1016/j.nephro.2018.02.011

[Evaluation of living kidney donors renal function]

Nephrol Ther. 2018 Apr:14 Suppl 1:S67-S72. doi: 10.1016/j.nephro.2018.02.011.

[Article in French]

Authors

François Gaillard¹, Marie Courbebaisse²

Affiliations

¹ Service de transplantation rénale, hôpital Necker, 145, rue de Sèvres, 75015 Paris, France; Université Paris Descartes, Sorbonne Paris Cité, 145, rue de Sèvres, 75015 Paris, France. Electronic address: gaillard-francois@hotmail.fr.
² Université Paris Descartes, Sorbonne Paris Cité, 145, rue de Sèvres, 75015 Paris, France; Service d'explorations fonctionnelles rénales, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris, France; Inserm unité 1151, 20, rue Leblanc, 75015 Paris, France.

PMID: 29606265
DOI: 10.1016/j.nephro.2018.02.011

Abstract

End-stage renal disease risk of living kidney donors is lower than the one in general population. In 2014, two independent studies confirmed this result but evidenced an increased risk of end-stage renal disease after donation. In this context, long-term consequences of living donation need to be better defined. Evaluation of renal function is a cornerstone of living donor screening. Precise knowledge of kidney donation physiology is required to propose a relevant predonation screening. In this review, we present the risks of donation, the physiology of living donation and discuss international guidelines.

Keywords: DFG; Donneurs vivants; GFR; Kidney; Living donors; Physiologie; Physiology; Rein; Risks; Risque.

Publication types

Review

MeSH terms

Humans
Kidney / physiology*
Kidney Failure, Chronic / epidemiology
Kidney Failure, Chronic / etiology*
Kidney Function Tests / methods*
Kidney Transplantation / adverse effects*
Living Donors
Risk