(18F)-FDG-PET/MRI of unicentric retroperitoneal Castleman disease in a pediatric patient

Negin Rassouli; Verena C Obmann; Linda M Sandhaus; Karin A Herrmann

doi:10.1016/j.clinimag.2018.03.010

(18F)-FDG-PET/MRI of unicentric retroperitoneal Castleman disease in a pediatric patient

Clin Imaging. 2018 Jul-Aug:50:175-180. doi: 10.1016/j.clinimag.2018.03.010. Epub 2018 Mar 13.

Authors

Negin Rassouli¹, Verena C Obmann², Linda M Sandhaus³, Karin A Herrmann⁴

Affiliations

¹ Department of Radiology, University Hospitals Cleveland Medical Center, Case Western Reserve University, 11100 Euclid Ave., Cleveland, OH 44106, USA.
² Department of Radiology, University Hospitals Cleveland Medical Center, Case Western Reserve University, 11100 Euclid Ave., Cleveland, OH 44106, USA; Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital Bern, Bern University Hospital, University of Bern, Freiburgstrasse 10, 3010 Bern, Switzerland. Electronic address: verena.obmann@UHhospitals.org.
³ Department of Pathology, University Hospitals Cleveland Medical Center, 11100 Euclid Ave., Cleveland, OH 44106, USA. Electronic address: linda.sandman@UHhospitals.org.
⁴ Department of Radiology, University Hospitals Cleveland Medical Center, Case Western Reserve University, 11100 Euclid Ave., Cleveland, OH 44106, USA. Electronic address: Karin.herrmann@uhhospitals.org.

PMID: 29604602
DOI: 10.1016/j.clinimag.2018.03.010

Abstract

Castleman disease (CD) is a rare lymphoproliferative disorder of unknown etiology that may occur anywhere in the lymphatic system. Imaging plays an important role in detecting and staging this disease. Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) combines the metabolic information derived from nuclear medical imaging with the high soft tissue resolution from MRI. We review the features of CD in standard diagnostic imaging, analyze the specific imaging findings of CD in FDG-PET/MRI and discuss a potential benefit of PET/MRI based on the case of a 15-year-old female patient with retroperitoneal CD.

Keywords: Castleman disease; Lymphoproliferative disorder; PET/MRI; Pediatric; Retroperitoneal mass.

Publication types

Case Reports

MeSH terms

Abdominal Neoplasms / diagnostic imaging
Abdominal Neoplasms / pathology
Adolescent
Castleman Disease / diagnostic imaging
Castleman Disease / pathology*
Female
Fluorodeoxyglucose F18
Humans
Magnetic Resonance Imaging / methods*
Male
Middle Aged
Neoplasm Staging
Peritoneum
Positron-Emission Tomography / methods*
Radiopharmaceuticals

Substances

Radiopharmaceuticals
Fluorodeoxyglucose F18