Iron oxide-doped niosomes as drug carriers for magnetically targeted drug delivery

Int J Nanomedicine. 2018 Mar 15;13(T-NANO 2014 Abstracts):7-9. doi: 10.2147/IJN.S125007. eCollection 2018.

Abstract

Magnetism has wide applications in various fields, such as diagnostics, drug targeting, molecular biology, cell isolation, cell purification, hyperthermia, and radioimmunoassay. In this study, we synthesized niosomes doped with iron oxide nanoparticles and a fluorophore for potential applications in magnetically targeted drug delivery. Release kinetics of the fluorophore and cytotoxicity were assessed. The results demonstrate that niosomes doped with iron oxide nanoparticles can serve as proficient and effective drug carriers in magnetically targeted drug delivery.

Keywords: drug carriers; fluorophores; iron oxide nanoparticles; magnetically targeted delivery; niosomes.

MeSH terms

  • A549 Cells
  • Drug Carriers / chemistry*
  • Drug Delivery Systems / methods*
  • Endocytosis
  • Ferric Compounds / chemistry*
  • Humans
  • Liposomes
  • Magnetics / methods*
  • Time Factors

Substances

  • Drug Carriers
  • Ferric Compounds
  • Liposomes
  • ferric oxide