Dissemination of carbapenem-resistant Klebsiella pneumoniae harboring KPC-carrying plasmid pKPC_P16, a pKPC_LK30 variant, in northern Taiwan

Diagn Microbiol Infect Dis. 2018 Jul;91(3):291-293. doi: 10.1016/j.diagmicrobio.2018.02.014. Epub 2018 Feb 22.

Abstract

The prevalence of carbapenem-resistant Klebsiella pneumoniae (CRKP) was up to 30% between 2014 and 2016 in the study hospital. Of these 77 CRKP isolates, 22 isolates with sequence type ST11 carried the new pKPC_P16 plasmid, a pKPC_LK30 variant, and were widely disseminated between 2014 and 2015 in northern Taiwan.

Keywords: Carbapenem-resistant Klebsiella pneumoniae; Klebsiella pneumoniae carbapenemase; Plasmid pKPC_P16; Sequence type ST 11; Taiwan.

MeSH terms

  • Carbapenems / pharmacology*
  • Cross-Sectional Studies
  • Genotype
  • Hospitals
  • Humans
  • Klebsiella Infections / epidemiology*
  • Klebsiella Infections / microbiology
  • Klebsiella pneumoniae / classification
  • Klebsiella pneumoniae / drug effects
  • Klebsiella pneumoniae / genetics
  • Klebsiella pneumoniae / isolation & purification*
  • Molecular Epidemiology
  • Molecular Typing
  • Plasmids / analysis
  • Prevalence
  • Sequence Analysis, DNA
  • Taiwan / epidemiology
  • beta-Lactam Resistance*

Substances

  • Carbapenems