Arterial stiffness and left ventricular performance in elderly patients with persistent atrial fibrillation

Aging Clin Exp Res. 2018 Nov;30(11):1403-1408. doi: 10.1007/s40520-018-0935-8. Epub 2018 Mar 22.

Abstract

Background: The prevalence of atrial fibrillation (AF) and arterial stiffness (AS) increases with age.

Aims: To evaluate if AS is correlated to longitudinal strain (LS), a marker of left ventricular (LV) function, in elderly AF patients with preserved ejection fraction (EF) undergoing external cardioversion.

Methods: AS was measured using the cardio-ankle vascular index (CAVI), LS was calculated from echocardiographic data of three consecutive cardiac cycles.

Results: We enrolled 38 patients (age 76 ± 8 years; men 60.5%; EF 65 ± 7%). LS and CAVI were, respectively, - 17.7 ± 3.7% and 9.7 ± 1.3. Multivariate analysis showed that LV performance was inversely related to height (p < 0.001) and to the presence of AF-related symptoms (p = 0.008). LS grew with increasing values of CAVI (p = 0.038).

Conclusions: In elderly AF patients with preserved systolic function, LV performance is directly associated with AS. This link could influence atrium remodeling and the incidence of arrhythmia relapse.

Keywords: Arterial stiffness; Atrial fibrillation; CAVI; Elderly; Electric cardioversion; Longitudinal strain.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Atrial Fibrillation / complications
  • Atrial Fibrillation / physiopathology*
  • Echocardiography
  • Electric Countershock
  • Female
  • Humans
  • Male
  • Multivariate Analysis
  • Vascular Stiffness*
  • Ventricular Function, Left*