High Concentration of Fluoride Can Be Increased Risk of Abortion

Biol Trace Elem Res. 2018 Oct;185(2):262-265. doi: 10.1007/s12011-018-1250-0. Epub 2018 Mar 14.

Abstract

The presence of fluoride in drinking water can be either beneficial or harmful for human health, depending on its concentration. Most adverse effects of fluoride are observed at high concentrations (above 1.5 mg/L). This study was aimed to evaluate the effect of fluoride concentrations in drinking water on spontaneous abortion in two regions: one with low fluoride concentration and another with high fluoride concentration. The results showed that there is a relationship between the concentration of fluoride in drinking water and abortion, so that the risk of abortion increased at high concentrations of fluoride. However, further studies are needed to clarify this relationship due to the small area and population in this study.

Keywords: Abortion; Drinking water; Fluoride; Iran.

MeSH terms

  • Abortion, Spontaneous / chemically induced*
  • Abortion, Spontaneous / epidemiology
  • Dose-Response Relationship, Drug
  • Drinking Water / chemistry*
  • Female
  • Fluorides / adverse effects*
  • Fluorides / analysis*
  • Humans
  • Iran / epidemiology
  • Pregnancy
  • Risk Factors

Substances

  • Drinking Water
  • Fluorides