Mutant IL-7Rα and mutant NRas are sufficient to induce murine T cell acute lymphoblastic leukemia

Leukemia. 2018 Aug;32(8):1795-1882. doi: 10.1038/s41375-017-0001-0. Epub 2018 Feb 15.

Sarah D Cramer^{1

2}, Julie A Hixon¹, Caroline Andrews¹, Ross J Porter^{1

3}, Gisele O L Rodrigues^{1

4

5}, Xiaolin Wu⁶, Tim Back¹, Kelli Czarra¹, Helen Michael⁷, Maggie Cam⁸, Jack Chen⁸, Dominic Esposito⁹, Emilee Senkevitch¹, Vijay Negi¹⁰, Peter D Aplan¹⁰, Wenqing Li¹, Scott K Durum¹¹

¹ Cytokines and Immunity Section, Cancer and Inflammation Program, National Cancer Institute (NCI), National Institutes of Health (NIH), Frederick, MD, USA.
² Department of Veterinary Medicine, University of Maryland, College Park, MD, USA.
³ School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, Scotland, UK.
⁴ Molecular Biology Laboratory, Boldrini Children's Center, Campinas, Brazil.
⁵ Department of Genetics, Evolution and Bioagents, Institute of Biology, State University of Campinas, Campinas, Brazil.
⁶ Genomics Laboratory, Cancer Research Technology Program, Leidos Biomedical Research, Inc. (LBR), Frederick National Laboratory for Cancer Research (FNLCR), Frederick, MD, USA.
⁷ Laboratory of Cancer Biology and Genetics, NCI, NIH, Bethesda, MD, USA.
⁸ Center for Cancer Research Collaborative Bioinformatics Resource, NCI, NIH, Bethesda, MD, USA.
⁹ Protein Expression Laboratory/RAS Reagents Core, NCI RAS Initiative, LBR, FNLCR, Frederick, MD, USA.
¹⁰ Leukemia Biology Section, Genetics Branch, NCI, NIH, Bethesda, MD, USA.
¹¹ Cytokines and Immunity Section, Cancer and Inflammation Program, National Cancer Institute (NCI), National Institutes of Health (NIH), Frederick, MD, USA. durums@mail.nih.gov.

No abstract available

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