Early-Stage Incorporation Strategy for Regioselective Labeling of Peptides using the 2-Cyanobenzothiazole/ 1,2-Aminothiol Bioorthogonal Click Reaction

Kuo-Ting Chen; Christian Ieritano; Yann Seimbille

doi:10.1002/open.201800016

Early-Stage Incorporation Strategy for Regioselective Labeling of Peptides using the 2-Cyanobenzothiazole/ 1,2-Aminothiol Bioorthogonal Click Reaction

ChemistryOpen. 2018 Feb 12;7(3):214. doi: 10.1002/open.201800016. eCollection 2018 Mar.

Authors

Kuo-Ting Chen¹, Christian Ieritano¹, Yann Seimbille¹

Affiliation

¹ Life Sciences Division TRIUMF Vancouver British Columbia V6T 2A3 Canada.

Abstract

Invited for this month's cover picture is the group of Dr. Yann Seimbille at the Life Sciences Division at TRIUMF (Canada). The cover picture shows how a simple and innovative methodology based on the bioorthogonal click reaction between 2-cyanobenzothiazole and 1,2-aminothiol has been elaborated to facilitate the labeling of peptide biovectors. Read the full text of their Communication at 10.1002/open.201700191.