Structural and functional brain network of human retrosplenial cortex

Panlong Li; Han Shan; Shengxiang Liang; Binbin Nie; Shaofeng Duan; Qi Huang; Tianhao Zhang; Xi Sun; Ting Feng; Lin Ma; Baoci Shan; Demin Li; Hua Liu

doi:10.1016/j.neulet.2018.03.016

Structural and functional brain network of human retrosplenial cortex

Neurosci Lett. 2018 May 1:674:24-29. doi: 10.1016/j.neulet.2018.03.016. Epub 2018 Mar 9.

Authors

Panlong Li¹, Han Shan², Shengxiang Liang¹, Binbin Nie³, Shaofeng Duan³, Qi Huang³, Tianhao Zhang³, Xi Sun¹, Ting Feng¹, Lin Ma², Baoci Shan⁴, Demin Li⁵, Hua Liu⁶

Affiliations

¹ Department of Physics, Zhengzhou University, Zhengzhou, Henan, 450001, China; Beijing Engineering Research Center of Radiographic Techniques and Equipment, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, 100049, China.
² Department of Radiology, Chinese People's Liberation Army General Hospital, Beijing, 100853, China.
³ Beijing Engineering Research Center of Radiographic Techniques and Equipment, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, 100049, China; School of Nuclear Science and Technology, University of Chinese Academy of Sciences, Beijing, 100049, China.
⁴ Beijing Engineering Research Center of Radiographic Techniques and Equipment, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, 100049, China; School of Nuclear Science and Technology, University of Chinese Academy of Sciences, Beijing, 100049, China; CAS Center for Excellence in Brain Science and Intelligence Technology, China. Electronic address: shanbc@ihep.ac.cn.
⁵ Department of Physics, Zhengzhou University, Zhengzhou, Henan, 450001, China. Electronic address: lidm@zzu.edu.cn.
⁶ Beijing Engineering Research Center of Radiographic Techniques and Equipment, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, 100049, China; School of Nuclear Science and Technology, University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: liuhua@ihep.ac.cn.

PMID: 29530816
DOI: 10.1016/j.neulet.2018.03.016

Abstract

Retrosplenial cortex (RSC) plays a key role in various cognitive functions. The fiber connectivity of RSC had been reported in rodent and primate studies by tracer injection methods To explore structural and functional connectivity of two sub-regions of RSC, Brodmann area (BA)29 and BA30, we constructed fiber connectivity networks of two sub-regions by diffusion tensor imaging (DTI) tractography based on diffusion magnetic resonance imaging (MRI) and functional connectivity networks by resting-state functional MRI. The BA29 network showed fiber connections with auditory cortex and functional connections with BA21. Both fiber and functional connections show that BA30 network includes visual cortex. Furthermore, BA30 had fiber connections with hippocampus, thalamus, and prefrontal cortex. We suggest that (1) structural connectivity reflects functional connectivity in some degree. (2) BA29 mainly received and processed sound information from auditory cortex, while BA30 mainly received and processed scene information from visual cortex.

Keywords: Cognitive function; DTI tractography; Functional MRI; Retrosplenial cortex.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Brain / anatomy & histology
Brain / physiology
Brain Mapping
Diffusion Tensor Imaging
Female
Gyrus Cinguli / anatomy & histology*
Gyrus Cinguli / physiology*
Humans
Magnetic Resonance Imaging
Male
Neural Pathways / anatomy & histology
Neural Pathways / physiology
Young Adult