Surgical Challenge in Pediatric Kidney Transplant Vascular Anastomosis

Exp Clin Transplant. 2018 Mar;16 Suppl 1(Suppl 1):14-19. doi: 10.6002/ect.TOND-TDTD2017.L41.

Abstract

During pediatric kidney transplant, surgical challenges occasionally occur. In particular, vascular anastomosis should be considered for children with small body weight < 12 kg, multiple renal arteries, vascular anomaly, and inferior vena cava occlusion. In pediatric patients, a living-donor renal graft is usually donated from a parent. Therefore, the renal artery and vein are too large to be anastomosed with the recipient's internal iliac artery and external iliac vein. In children who are > 12 kg, the renal artery and vein could be anastomosed with the external iliac artery and the external iliac vein. In children who are < 10 kg, the renal artery and vein should be anastomosed directly with the aorta and inferior vena cava. A pediatric transplant surgeon should consider arterial and venous anastomosis sites before transplant surgery. In small children with partial or total inferior vena cava occlusion, the venous anastomosis site should be evaluated. If the graft is placed on the left side, a venous graft must be used as a bridge between the renal vein and inferior vena cava. In 13 kidney transplants in children with inferior vena cava occlusion, 7 were on the left and 6 were on the right side. A patent segment of the inferior vena cava, the left original renal vein, an ascending lumbar vein, an azygos vein, the first graft renal vein, and a portal vein were used for venous anastomosis in 6, 2, 2, 1, 1 and 1 recipient, respectively. One child had graft loss due to renal vein thrombosis and one died of hemorrhage immediately posttransplant. Three had grafts with relatively long-term function, but these were lost due to chronic allograft nephropathy 100, 122, and 137 months posttransplant. However, the other 8 recipients have so far maintained graft function from 6 to 138 months since transplant.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Age Factors
  • Anastomosis, Surgical
  • Aorta / diagnostic imaging
  • Aorta / physiopathology
  • Aorta / surgery
  • Aortography / methods
  • Azygos Vein / diagnostic imaging
  • Azygos Vein / physiopathology
  • Azygos Vein / surgery
  • Body Weight
  • Child
  • Child, Preschool
  • Computed Tomography Angiography
  • Female
  • Graft Occlusion, Vascular / etiology
  • Graft Occlusion, Vascular / physiopathology
  • Humans
  • Iliac Artery / diagnostic imaging
  • Iliac Artery / physiopathology
  • Iliac Artery / surgery
  • Iliac Vein / diagnostic imaging
  • Iliac Vein / physiopathology
  • Iliac Vein / surgery
  • Kidney Transplantation / adverse effects
  • Kidney Transplantation / methods*
  • Living Donors*
  • Male
  • Phlebography / methods
  • Portal Vein / diagnostic imaging
  • Portal Vein / physiopathology
  • Portal Vein / surgery
  • Renal Artery / diagnostic imaging
  • Renal Artery / physiopathology
  • Renal Artery / transplantation*
  • Renal Veins / diagnostic imaging
  • Renal Veins / physiopathology
  • Renal Veins / transplantation*
  • Risk Factors
  • Time Factors
  • Treatment Outcome
  • Vascular Patency
  • Vascular Surgical Procedures* / adverse effects
  • Vena Cava, Inferior / diagnostic imaging
  • Vena Cava, Inferior / physiopathology
  • Vena Cava, Inferior / surgery