The migrasome is a newly discovered, migration-dependent membrane-bound cellular organelle. It functions in the active release of intracellular contents into the external environment and in cell-cell communications. Migrasomes have characteristic morphological features compared with intracellular organelles and extracellular vesicles. This unit describes methods for visualizing migrasomes by fluorescence microscopy and electron microscopy.
Keywords: Cell–cell communication; Fibronectin; Fluorescence microscopy; Migracytosis; Migrasome; Migration; Transmission electron microscopy.